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Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium

Burkert Pieske, Lars S Maier, Valentino Piacentino, Jutta Weisser, Gerd Hasenfuss, Steven Houser
In the failing human heart, altered Ca2+ homeostasis causes contractile dysfunction. Because Ca2+ and Na+ homeostasis are intimately linked through the Na+/Ca2+ exchanger, we compared the regulation of [Na+]i in nonfailing (NF) and failing human myocardium
Článek, 2002
Circulation, 106, 20020723, 447
2002