Acids and Bases : Solvent Effects on Acid-Base Strength
Acids and bases are ubiquitous in chemistry. Our understanding of them, however, is dominated by their behaviour in water. Transfer to non-aqueous solvents leads to profound changes in acid-base strengths and to the rates and equilibria of many processes: for example, synthetic reactions involving acids, bases and nucleophiles; isolation of pharmaceutical actives through salt formation; formation of zwitter- ions in amino acids; and chromatographic separation of substrates. Thisbook seeks to enhance our understanding of acids and bases by reviewing and analysing their behaviour in non-aqueous
Elektronická kniha, English, 2013
OUP Oxford, Oxford, 2013