Cancer -- Between Glycolysis and Physical Constraint
Considerable effort has gone into the research of common cancers - lung, bowel, ovarian, cervical, and prostate cancer. In recent years, however, there has been a lack of breakthroughs in therapeutic advances. By challenging many established beliefs, Cancer explores these issues by offering new perspectives on the study of cancer and exploring the areas of mathematics, physics and chemistry in cancer research. This book is for cancer specialists, clinicians, and researchers interested in an innovative view in cancer research
eBook, English, 2004
Springer Berlin Heidelberg : Imprint : Springer, Berlin, Heidelberg, 2004
1 online resource (XVIII, 150 pages 5 illustrations)
9783642185434, 9783540204961, 3642185436, 3540204962
840291519
Introduction
Are Cancer Cells Malignant Per Se?- Cell Growth: a Balance Between Glycolysis and Physical Constraint
Extracellular Constraints Regulate Cell Differentiation
Changes in Cellular Constraints During Carcinogenesis
Hypoxia is Responsible for Changes in Cellular Constraints During Inflammation
Fibrosis Perpetuates Hypoxia
Metastasis: the Hunt for Food
Carcinogens Target Cell Respiration and Induce Glycolysis
Epidemiology: Aging as the Main Cause of Cancer
Aging Causes Inflammation and Fibrosis Mimicking the Impact of Carcinogens
Inhibition of Metabolism Slows Aging and Decreases Cancer Incidence
A Complication of Hypoxia: the Loss of Cell Polarity Explains Cancer Cell Proliferation
The Loss of Cell Differentiation is a Consequence of Glycolysis
Response to Treatment: a Balance Between Glycolysis and Physical Constraints
Targeting Glycolysis
Conclusion
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