Front cover image for A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen

Peer-reviewed

A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen

J J J Fu, G G Hillebrand, P Raleigh, J Li, M J Marmor, V Bertucci, P E Grimes, S H Mandy, M I Perez, S H Weinkle, J R Kaczvinsky
Tretinoin is considered the benchmark prescription topical therapy for improving fine facial wrinkles, but skin tolerance issues can affect patient compliance. In contrast, cosmetic antiwrinkle products are well tolerated but are generally presumed to be less efficacious than tretinoin
Article, 2010
The British journal of dermatology, 162, 201003, 647
2010