Peer-reviewed
Precision Oncology, Signaling, and Anticancer Agents in Cancer Therapeutics
Background: The global alliance for genomics and healthcare facilities provides innovative solutionsto expedite research and clinical practices for complex and incurable health conditions. Precision oncology is anemerging field explicitly tailored to facilitate cancer diagnosis, prevention, and treatment based on patientsgenetic profiles. Advancements in “omics” techniques, next-generation sequencing, artificial intelligence, andclinical trial designs provide a platform for assessing the efficacy and safety of combination therapies anddiagnostic procedures. Method: Data were collected from PubMed and Google Scholar using keywords “Precision medicine,”“precision medicine and cancer,” “anticancer agents in precision medicine,” and reviewed comprehensively. Results: Personalized therapeutics, including immunotherapy and cancer vaccines, serve as a groundbreakingsolution for cancer treatment. Herein, we take a measurable view of precision therapies and novel diagnosticapproaches targeting cancer treatment. The contemporary applications of precision medicine have also beendescribed, along with various hurdles identified in the successful establishment of precision therapeutics. Conclusion: This review highlights the key breakthroughs related to immunotherapies, targeted anticanceragents, and target interventions related to cancer signaling mechanisms. The success story of this field in contextto drug resistance, safety, patient survival, and improving quality of life is yet to be elucidated. We conclude that,in the near future, the field of individualized treatments may truly revolutionize the nature of cancer patient care
Downloadable Article
Anti-Cancer Agents in Medicinal Chemistry: ACAMC, 22, 2022